Naslov (eng)

Bioinformatics identification of extracellular vesicle-derived microRNAs biomarkers in pancreatic cancer

Autor

Janjić, Filip
Janković, Tamara
Mitić, Ninoslav
Janković, Miroslava
Dobrijević, Zorana
Goč, Sanja

Publisher

Opis (eng)

ABSTRACT Pancreatic cancer is one of the most lethal malignancies worldwide due to the lack of effective early diagnostic tools and its asymptomatic early stages. It is the 6th leading cause of cancer-related mortality, with a 5-year survival rate ranging from 44% in localized disease to 3% in metastatic cases. CA19-9, the most commonly used biomarker, has limited sensitivity and low positive predictive value, restricting its use in screening. Therefore, novel biomarkers are needed, and extracellular vesicle-associated miRNAs (EV-miRNAs) are increasingly recognized for their stability and potential in non-invasive cancer diagnosis.

Jezik

engleski

Datum

2026

Licenca

Ovo delo je licencirano pod uslovima licence
Creative Commons CC BY-NC-ND 4.0 - Creative Commons Autorstvo - Nekomercijalno - Bez prerada 4.0 International License.

http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode

Predmet

Extracellular vesicles, microRNA, Pancreatic cancer

Deo kolekcije (1)

o:25140

Radovi Instituta za primenu nuklearne energije - INEP