Interspecies Communication via Extracellular Vesicles: A Promising Strategy for Treating Respiratory Allergy
Glamočlija Jekić, Sofija
Shmid, Anna
Radulović, Nataša
Gruden-Movsesijan, Alisa
Sabljić, Ljiljana
Tomić, Sergej
Djokić, Jelena
Schabussova, Irma
Kosanović, Maja
ABSTRACT Extracellular vesicles (EVs) released by parasitic organisms represent a fascinating frontier in interspecies communication, serving as nanoscale couriers that deliver regulatory cargo to modulate host immune responses and ensure parasite survival. Across diverse phyla, from protozoans deploying EVs to evade innate immunity, to trematodes using them to dampen inflammation, EVs exploit conserved uptake pathways in mammalian cells, reprogramming signaling in recipient cells which can lead to tolerance and alleviate pathology.
engleski
2026
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extracellular vesicles, respiratory allergy