Naslov (eng)

Trichinellosis: A zoonosis that still requires vigilance

Autor

Gruden-Movsesijan, Alisa
Mitić, Ivana
Vasilev, Saša

Publisher

PLOS

Opis (eng)

ABSTRACT Trichinellosis is a parasitic disease in humans caused by nematodes of the genus Trichinella, usually acquired through the consumption of raw or undercooked meat, mainly from pigs or wild animals, containing infective larvae. Although often overlooked, this disease has affected humans for centuries and continues to be a public health concern in many parts of the world, especially where food safety measures are inadequate. In this millennium, significant progress has been made in understanding the disease pathophysiology and host immune response, mainly through experimental studies in rodents, while human pathophysiology and immune response still await elucidation. This review integrates current knowledge on the biology, transmission, and manifestations of trichinellosis, as well as challenges in diagnosis, treatment, and prevention. The parasite’s life cycle involves an initial intestinal phase followed by systemic migration of larvae into striated muscles, where long-lasting cysts are established. The clinical presentation varies from mild gastrointestinal discomfort to severe systemic manifestations such as fever, periorbital edema, and muscle pain. In some cases, chronic symptoms, including fatigue and reduced muscle strength, may persist for years.

Jezik

engleski

Datum

2026

Licenca

Creative Commons licenca
Ovo delo je licencirano pod uslovima licence
Creative Commons CC BY 4.0 - Creative Commons Autorstvo 4.0 International License.

http://creativecommons.org/licenses/by/4.0/legalcode

Predmet

Trichinella, infection, trichinellosis

Deo kolekcije (1)

o:25140 Radovi Instituta za primenu nuklearne energije - INEP