Naslov (eng)

Noncoding RNAs as biomarkers of gestational diabetes mellitus

Autor

Dobrijević, Zorana
Stevanović, Jovana

Publisher

Opis (eng)

Non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), show potential to serve as biomarkers of metabolic disorders, oxidative stress and inflammatory status, and thus may have diagnostic and prognostic significance in gestational diabetes mellitus (GDM). Aberrant expression of specific ncRNAs has been identified in placental tissue, plasma, serum, extracellular vesicles, peripheral blood mononuclear cells (PBMCs), as well as in other maternal and fetal sources. These ncRNAs exhibit high stability in circulation and can reflect underlying molecular alterations, making them promising non-invasive biomarkers for diagnosis, prognosis, and disease monitoring. Therefore, this article will review the major findings of GDM-related ncRNAs and highlight their potential role in improving clinical outcomes through biomarker-based approaches.

Jezik

engleski

Datum

2025

Licenca

Ovo delo je licencirano pod uslovima licence
Creative Commons CC BY 4.0 - Creative Commons Autorstvo 4.0 International License.

http://creativecommons.org/licenses/by/4.0/legalcode

Predmet

gestational diabetes mellitus, miRNA, lncRNA, circRNA, liquid biopsy

Deo kolekcije (1)

o:25140

Radovi Instituta za primenu nuklearne energije - INEP