Naslov (eng)

Trichinella spiralis-derived extracellular vesicles induce regulatory T cells and reduce airway allergy in mice

Autor

Glamočlija, Sofija
Kosanović, Maja
Schabussova, Irma
Wiedermann, Ursula
Inić-Kanada, Aleksandra
Vasilev, Saša
Gruden-Movsesijan, Alisa
Radulović, Nataša
Schmid, Anna
Sabljić, Ljiljana

Publisher

Opis (eng)

ABSTRACT Introduction: Respiratory allergies are an increasing global health concern, with current treatments primarily targeting symptoms rather than underlying immune dysregulation. Trichinella spiralis derived extracellular vesicles (TsEVs) have been implicated in modulating immune responses, but their role in allergic airway inflammation remains unexplored. This study investigates the immunomodulatory potential of TsEVs in mitigating ovalbumin (OVA)-induced allergic airway inflammation in mice. Methods: TsEVs were isolated from T. spiralis muscle larvae excretory-secretory products and characterized using nanoparticle tracking analysis.

Jezik

engleski

Datum

2025

Licenca

Ovo delo je licencirano pod uslovima licence
Creative Commons CC BY 4.0 - Creative Commons Autorstvo 4.0 International License.

http://creativecommons.org/licenses/by/4.0/legalcode

Predmet

Trichinella spiralis, extracellular vesicles, respiratory allergy, regulatory T cells, immune modulation, allergic inflammation

Deo kolekcije (1)

o:25140

Radovi Instituta za primenu nuklearne energije - INEP