Naslov (eng)

Characterisation of thyroid-originating extracellular vesicles from thyroid cell culture medium and plasma of patients harboring thyroid tumors

Autor

Janković Miljuš, Jelena
Šelemetjev, Sonja
Žarković, Miloš
Živaljević, Vladan
Išić Denčić, Tijana
Djorić, Ilona
Kosanović, Maja
Mitić, Ninoslav

Publisher

Opis (eng)

ABSTRACT Introduction: Postoperative follow-up of differentiated thyroid carcinoma patients based on measuring thyroglobulin (Tg) levels is unreliable in patients with Tg autoantibodies (TgAt). Detecting thyroid markers on extracellular vesicles (EVs) might be a potent way to overcome these issues. We analysed the presence of CD63 (EVs marker) and thyroid-specific markers: thyroid-stimulating hormone receptor (TSHR) and Tg in EVs of thyroid cell lines to optimize detection and later in plasma EVs of thyroid nodule patients.

Jezik

engleski

Datum

2024

Licenca

© All rights reserved

Predmet

Thyroid cancer follow-up, recurrent thyroid cancer, extracellular vesicles, thyroglobulin, TSHR

Deo kolekcije (1)

o:25140

Radovi Instituta za primenu nuklearne energije - INEP