Naslov (eng)

Minimal information for studies of extracellular vesicles (MISEV2023); From basic to advanced approaches

Autor

Welsh, Joshua A.
Goberdhan, Deborah C. I.
O'Driscoll, Lorraine
Buzas, Edit I.
Blenkiron, Cherie
Bussolati, Benedetta
Cai, Houjian
Di Vizio, Dolores
Driedonks, Tom A. P.
Erdbrügger, Uta
Falcon-Perez, Juan M.
Fu, Qing-Ling
Hill, Andrew F.
Lenassi, Metka
Kiang Lim, Sai
Mahoney, Mỹ G.
Mohanty, Sujata
Möller, Andreas
Nieuwland, Rienk
, et al.

Doprinosi

Kosanović, Maja
Glamočlija, Sofija

Publisher

Opis (eng)

ABSTRACT Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its ‘Minimal Information for Studies of Extracellular Vesicles’, which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues.

Jezik

engleski

Datum

2024

Licenca

Ovo delo je licencirano pod uslovima licence
Creative Commons CC BY 4.0 - Creative Commons Autorstvo 4.0 International License.

http://creativecommons.org/licenses/by/4.0/legalcode

Predmet

ctosomes, exosomes, extracellular vesicles, extracellular particles, guidelines, microparticles, microvesicles, minimal information requirements, MISEV, reproducibility, rigor, standardisation

Deo kolekcije (1)

o:25140

Radovi Instituta za primenu nuklearne energije - INEP