Naslov (eng)

LncRNAs Involved in Antioxidant Response Regulation as Biomarkers of Gestational Diabetes: A Study on H19, MALAT1 and MEG3

Autor

Stevanović, Jovana
Petrović, Uroš
Penezić, Ana
Radojičić, Ognjen
Ardalić, Daniela
Mandić, Milica
Mandić-Marković, Vesna
Miković, Željko
Brkušanin, Miloš
Nedić, Olgica
Dobrijević, Zorana

Publisher

Opis (eng)

ABSTRACT Recent findings highlighted the potential of long non-coding RNAs (lncRNAs) as novel indicators of gestational diabetes mellitus (GDM), as they demonstrate altered expression in metabolic disorders, oxidative stress (OS) and inflammation (IFM). The aim of this study was to evaluate the diagnostic potential and prognostic significance of the OS/IFM-related lncRNAs H19, MALAT1 and MEG3 in GDM and their correlations with redox status-related parameters. The relative quantification of selected lncRNAs from peripheral blood mononuclear cells (PBMCs) of GDM patients and controls (n= 50 each) was performed by qPCR.

Jezik

engleski

Datum

2024

Licenca

Ovo delo je licencirano pod uslovima licence
Creative Commons CC BY 4.0 - Creative Commons Autorstvo 4.0 International License.

http://creativecommons.org/licenses/by/4.0/legalcode

Predmet

H19; MALAT1; MEG3; oxidative stress; redox status; inflammation; gestational diabetes; zinc; glutathione reductase; thiol content

Deo kolekcije (1)

o:25140

Radovi Instituta za primenu nuklearne energije - INEP