Naslov (eng)

DESIGN AND EVALUATION OF LIPOSOMAL FORMULATION OF CAROB (Ceratonia siliqua L.) PULP EXTRACT

Autor

Dekanski, Dragana
Rašković, Aleksandar
Martić, Nikola
Pirković, Andrea
Jovanović, Aleksandra

Publisher

Opis (eng)

The carob (Cerationa siliqua L.) pulp flour is used primarily in the food industry. As a valuable source of bioactive compounds (polyphenols), it is a good candidate for pharmaceutical formulation research and development. In this study, carob pulp extract-loaded liposomal particles were developed using the proliposome procedure and characterized via encapsulation efficiency (EE), vesicle size, polydispersity index (PDI), zeta potential, mobility, and viscosity. The obtained results suggest that the EE is high (80.6±3.3%). The particle size and PDI results indicated the existence of the multilamellar and uniform liposomal system. Lower values of zeta potential and mobility (-17.8±1.0 mV and -1.40±0.08 µmcm/Vs, respectively) of developed liposomes suggest that future experiments should be focused on the carob pulp liposomal nutraceutical formulation improvement, particularly its stability.

Jezik

engleski

Datum

2024

Licenca

Ovo delo je licencirano pod uslovima licence
Creative Commons CC BY-NC-SA 4.0 - Creative Commons Autorstvo - Nekomercijalno - Deliti pod istim uslovima 4.0 International License.

http://creativecommons.org/licenses/by-nc-sa/4.0/legalcode

Deo kolekcije (1)

o:25140

Radovi Instituta za primenu nuklearne energije - INEP