Potential Influence of miR-204-3P on ETS-1 Protein Expression in Papillary Thyroid Carcinoma
Stojanović, Stefana
Išić Denčić, Tijana
Milinković, Marija
Tausanović, Katarina
Janković Miljuš, Jelena
Đorić, Ilona
Šelemetjev, Sonja
ABSTRACT Objectives: ETS-1 (E26 transformation-specific) is a transcription factor associated with the progression of carcinomas of various origins. Its expression in PTC is poorly described, and the findings are controversial. This study aimed to describe ETS-1 protein expression in papillary thyroid carcinoma (PTC) and to evaluate the potential influence of miR-204-3p on the ETS-1 protein expression in PTC since the bioinformatic analysis revealed that miR-204-3p shares a seed sequence with the 3’-untranslated region (3’UTR) of ETS-1 mRNA.
engleski
2024
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ETS-1 protein expression, papillary thyroid carcinoma (PTC)