Comparative analysis of surface glycosylation of prostasomes from human seminal plasma of normozoospermic and asthenozoospermic men
ABSTRACT Introduction: Seminal prostasomes are extracellular vesicles secreted by prostate epithelial cells. Using lectin affinity-chromatography, previous studies showed that mannosylated and sialylated glycans contribute to the prostasomal surface. Taking advantage of nanoparticle tracking analysis (NTA), we further investigated the difference of surface glycosylation and size distribution of prostasomes isolated from seminal plasma of normozoospermic (sProN) and asthenozoospermic (sProA) men.
engleski
2024
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nano tracking analysis, prostasomes, glycosylation, lectins, tetraspanins