Effects of IGF-1 on the IGFB proteins level in the serum of obese male rats
Obradović, Milan
Isenović, Esma
Nedić, Olgica
Gligorijević, Nikola
Banjac, Katarina
Šunderić, Miloš
Zafirović, Sonja
ABSTRACT Insulin-like growth factor binding (IGFB) proteins are a group of six highly conserved proteins that bind to insulin-like growth factors (IGFs) and transport them through the bloodstream to the target cells. The IGFB proteins play an important role in regulating IGF signaling pathways by lengthening their half-life. Obesity and associated disorders are linked to abnormal levels of IGFB proteins. Thus, this study aimed to evaluate how IGF-1 affects the levels of IGFB proteins in the serum of obese rats.
engleski
2024
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Creative Commons CC BY-NC-ND 4.0 - Creative Commons Autorstvo - Nekomercijalno - Bez prerada 4.0 International License.
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IGF-1, IGFBP, serum, rats