Naslov (eng)

Caffeic acid downregulates HIF1A and VEGF receptors modulating endothelial-like properties of human trophoblast cells

Autor

Vilotić, Aleksandra
Dekanski, Dragana
Jovanović Krivokuća, Milica

Publisher

Opis (eng)

ABSTRACT Caffeic acid (CA) is a polyphenolic compound widely present in fruits, vegetables, spices and beverages used in everyday diet. Numerous research indicated beneficial effects of CA on human health including its antioxidant, anti-inflammatory and anticancer activities. Nevertheless, data about the effects of CA in pregnancy, especially on early pregnancy events, are limited. Remodeling of uterine spiral arteries together with trophoblast endovascular differentiation are critical processes for establishing and maintaining a healthy pregnancy. The aim of this study is to investigate how CA affects trophoblast endothelial-like properties assessed with tube formation assay on Matrigel, an in vitro angiogenesis assay.

Jezik

engleski

Datum

2024

Licenca

Ovo delo je licencirano pod uslovima licence
Creative Commons CC BY-NC-ND 4.0 - Creative Commons Autorstvo - Nekomercijalno - Bez prerada 4.0 International License.

http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode

Deo kolekcije (1)

o:25140

Radovi Instituta za primenu nuklearne energije - INEP