Naslov (eng)

Analysis of salivary constituents in healthy and Sjögren syndrome patients

Autor

Hadži-Mihailović, Miloš
Stanimirović, Dragan
Bojić-Trbojević, Žanka
Golubović, Snežana

Opis (eng)

ABSTRACT Sjögren’s syndrome (SS) is a complex autoimmune disease, characterized by a progressive hypofunction and inflammation of salivary and lachrymal glands. Diagnosis of SS is problematic, because it often relies on nonspecific signs and symptoms with no specific biomarker(s). Since saliva directly reflects salivary gland inflammation and damage, this body fluid appeared as useful tool for new biomarker research. In the last few years, salivary proteomic studies were conducted providing considerable contribution in the search of SS biomarkers. As a body fluid, saliva contain a number of glycosylated proteins, including heavily glycosylated carcinoembryonic antigen (CEA), described as inflammatory protein. This study aimed to investigate salivary proteome and CEA as a potential salivary biomarker in Sjögren’s syndrome patients.

Jezik

engleski

Datum

2021

Licenca

Ovo delo je licencirano pod uslovima licence
Creative Commons CC BY 4.0 - Creative Commons Autorstvo 4.0 International License.

http://creativecommons.org/licenses/by/4.0/legalcode

Predmet

Sjögren’s syndrome, biomarkers, saliva

Deo kolekcije (1)

o:25140

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