Naslov (eng)

Thyroglobulin detection in extracellular vesicles isolated from human plasma

Autor

Đorić, Ilona
Janković Miljuš, Jelena
Kosanović, Maja
Išić Denčić, Tijana
Živaljević, Vladan
Šelemetjev, Sonja

Publisher

Opis (eng)

ABSTRACT Detecting recurrence of differentiated thyroid cancer is performed by serial measurements of serum thyroglobulin (Tg) levels, however, in the presence of anti-Tg antibodies, this measurement is unreliable. Extracellular vesicles (EVs) are small membrane-enclosed structures, with a prominent role in cell-to-cell communication. All cell types release EVs and they can be isolated from various biofluids, while their cargo reflects the content of the cell of origin. Previous studies showed that EVs from bovine serum, FRTL-6 rat thyroid cell line conditioned medium and human urine all contain thyroglobulin. EVs isolated from human serum were not previously investigated for the presence of Tg.

Jezik

engleski

Datum

2023

Licenca

Ovo delo je licencirano pod uslovima licence
Creative Commons CC BY 4.0 - Creative Commons Autorstvo 4.0 International License.

http://creativecommons.org/licenses/by/4.0/legalcode

Predmet

thyroid cancer, extracellular vesicles, nanoparticle tracking analysis

Deo kolekcije (1)

o:25140

Radovi Instituta za primenu nuklearne energije - INEP